The Budding Yeast Saccharomyces cerevisiae as a Model System for Anti-Cancer Drug Screening

The yeast Saccharomyces cerevisiae is widely used as a model organism to investigate many as- pects of eukaryotic cell biology. It has a high level of conservation between its cellular processes and those of mammalian cells with advantages such as simple growth requirements and rapid cell division. Moreover, it is a genetically tractable organism, amenable to modifications such as gene disruption, gene marking and protein-protein interaction with the yeast two-hybrid system. Up to now, yeast has maintained its role as a useful model system for fundamental studies related to dis- ease processes...