Neoadjuvant Chemotherapy for Urothelial Muscle-Invasive Bladder Cancer: Influence of Body Mass Index on Efficacy and Toxicity

Neoadjuvant Chemotherapy for Urothelial Muscle-Invasive Bladder Cancer: Influence of Body Mass Index on Efficacy and Toxicity

1. Abstract

1.1. Background: Neoadjuvant Chemotherapy (NAC) and radical cystectomy with pelvic lymph node dissection are the cornerstone of therapy for patients with Muscle Invasive Bladder Cancer

(MIBC). We assessed the potential influence of body mass index (BMI) on toxicity and efficacy of NAC in patients with MIBC.