Chronopharmacokinetics Variation of Doxorubicin in a Pediatric Patient with Osteosarcoma Triggers Adverse Effects

1. Abstract

1.1. Aims: This is a case report that exemplifies the chronopharmacokinetic differences of Doxorubicin (Dox), depending on time of administration of the drug because of biological rhythms, and its repercussions on adverse reactions.