Metastatic Colorectal Cancer in two Young Patients with Inflammatory Bowel Disease – Relevance of Tight Endoscopic Surveillance Especially in Early-Onset IBD and Review of the Literature

Metastatic Colorectal Cancer in two Young Patients with Inflammatory Bowel Disease – Relevance of Tight Endoscopic Surveillance Especially in Early-Onset IBD and Review of the Literature

1. Abstract

1.1. Background: The Risk of Colorectal Cancer (CRC) in Inflammatory Bowel Diseases patients (IBD) is still higher than in the general population. In this report, we present two cases of early-onset and longstanding, highly active IBD (one patient with Crohn`s Disease (CD), one patient with Ulcerative Colitis (UC)), who developed metastatic CRC at a young age due to lack of surveillance endoscopies and suboptimal medical treatment and correlate our findings with available literature.