Reversible Dementia Induced by VEGFR-Tkis: A Case Report and Literature Review

1. Abstract
1.1. Background: Vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs) are widely used in patients with malignancies and common adverse events are well known by clinical oncologist. However, uncommon adverse events especially neuotoxicity are known little and there was no report of reversible dementia caused by VEGFR-TKIs to date.