Construction and Validation of Prognostic Signature Model Based on Metastatic Features for Colorectal Cancer

1. Abstract
1.1. Background: Colorectal Cancer (CRC) is a common malignant cancer with a poor prognosis. Liver metastasis is the dominant cause of death in CRC patients, and it often involves changes in various gene expression profiling. This study proposed to construct and validate a risk model based on differentially expressed genes between the primary and liver metastatic tumors from CRC for prognostic prediction.